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NSC 405020

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MT1-MMP 抑制剂

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产品目录号: A13072

库存状态:中国现货中国现货

产品名 目录号 价格 数量
NSC 405020 10mg A13072-10
¥ 550.00
NSC 405020 25mg A13072-25
¥ 1,100.00
NSC 405020 50mg A13072-50
¥ 2,100.00
NSC 405020 100mg A13072-100
¥ 3,600.00
NSC 405020 10mM * 1mL in DMSO A13072-10mM-D
¥ 750.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

NSC-405020 is a membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L).

NSC 405020

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 NSC 405020 发表的文献 (1)
  • Kittaka M, .et al. Cherubism Mice Also Deficient in c-Fos Exhibit Inflammatory Bone Destruction Executed by Macrophages That Express MMP14 Despite the Absence of TRAP+ Osteoclasts, J Bone Miner Res, 2018, Jan;33(1):167-181 PMID: 28914985

Chemical Information

目录号 A13072
Mechanism of action Inhibitor
分子量 260.16
化学分子式 C12H15Cl2NO
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. CAS: 7497-07-6
Synonyms NSC405020, NSC-405020
SMILES code CCCC(C)NC(=O)C1=CC(=C(C=C1)Cl)Cl
化学名称 3,4-Dichloro-N-(1-methylbutyl)benza?mide

生物活性

Description
NSC-405020 is a membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L).
Targets
MT1-MMP

溶解性

Solubility (25°C) * In vitro DMSO 52 mg/mL (199.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol 52 mg/mL (199.87 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.44 mL 192.19 mL 384.38mL
0.5 mM 7.69 mL 38.44 mL 76.88 mL
1 mM 3.84 mL 19.22 mL 38.44 mL
5 mM 0.77 mL 3.84 mL 7.69 mL

*The above data is based on the productmolecular weight 260.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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