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b-AP15 (NSC 687852)

b-AP15 (NSC 687852)

Name: b-AP15 (NSC 687852)
SKU: A15391

目录号: A15391

DUB 抑制剂

Product Citations (1)

b-AP15 (NSC 687852) Chemical Structure

CAS NO. 1009817-63-3

b-AP15 (NSC 687852)是两种与蛋白酶体相关的DUBs的泛素特异性加工蛋白酶14（USP14）和泛素羧基末端水解酶同工酶L5（UCHL5）的抑制剂。

库存：现货

规格	价格	数量
10 mg	￥ 550.00
25 mg	￥ 900.00
50 mg	￥ 1,350.00

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生物活性

b-AP15 (NSC 687852)是两种与蛋白酶体相关的DUBs的泛素特异性加工蛋白酶14（USP14）和泛素羧基末端水解酶同工酶L5（UCHL5）的抑制剂。

靶点信息

USP14	UCHL5
N/A	2.1 μM

溶解度 *

In vitro (25°C)	DMSO	Warmed: 42 mg/mL (100.14 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+corn oil	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.84 mL	119.22 mL	238.44 mL
0.5 mM	4.77 mL	23.84 mL	47.69 mL
1 mM	2.38 mL	11.92 mL	23.84 mL
5 mM	0.48 mL	2.38 mL	4.77 mL

*The above data is based on the productmolecular weight 419.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15391
作用机制	Inhibitor (抑制剂)
M. Wt	419.39
Formula	C22H17N3O6
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1009817-63-3
Synonyms	b-AP15
SMILES	C=CC(=O)N1CC(=CC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(=CC3=CC=C(C=C3)[N+](=O)[O-])C1