|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||37.7 mL||188.49 mL||376.97 mL|
|0.5 mM||7.54 mL||37.7 mL||75.39 mL|
|1 mM||3.77 mL||18.85 mL||37.7 mL|
|5 mM||0.75 mL||3.77 mL||7.54 mL|
*The above data is based on the productmolecular weight 265.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Activator|
|Storage||at -20°C 3 years Powder|
|Synonyms||NSC 59984, NSC-59984|
p53 and MDM2 proteins-interaction-inhibitor chiral is an inhibitor of the interaction between p53 and MDM2 proteins.
RITA, also referred to as NSC 652287, is a trycyclic thiophene derivative that binds to MDM2, disrupting the MDM2-p53 complex and subsequent…
WR 1065, a dephosphorylated metabolite of amifostine (Ethyol), can protect against the immediate and delayed effects of radiation exposure.
RETRA hydrochloride is an antitumor agent which inhibits tumor cell growth in a mutant p53- and p73-dependent manner in vitro and iin vivo.
NSC 146109 hydrochloride is a cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription.