NSC87877
目录号: A16120
SHP 抑制剂
NSC-87877 是一种能够渗透细胞的抑制剂，它同时抑制 SHP-1 和 SHP-2，其 IC50 值分别为 355 nM 和 318 nM。
顾客使用 Adooq 产品发表的高质量科研文献
生物活性
| Discription | NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. | ||
|---|---|---|---|
| Targets |
|
产品信息
| 目录号 | A16120 |
|---|---|
| 分子式 | C19H13N3O7S2.2Na |
| 分子量 | 503.42 |
| CAS号 | 56932-43-5 |
| SMILES | C1=CC2=C(C(=O)C(=NNC3=CC4=C(C=C3)C=C(C=C4)S(=O)(=O)[O-])C=C2S(=O)(=O)[O-])N=C1.[Na+].[Na+] |
| 其他名称 | NSC-87877, NSC 87877 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 85 mg/mL (168.84 mM) | |
| Water | 85 mg/mL (168.84 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+35% PEG 300+2% Tween 80+ddH2O | 5 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.86 mL | 99.32 mL | 198.64 mL |
| 0.5 mM | 3.97 mL | 19.86 mL | 39.73 mL |
| 1 mM | 1.99 mL | 9.93 mL | 19.86 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.97 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 NSC87877 | NSC87877 供应商 | NSC87877 花费 | NSC87877 生产商 | 订购 NSC87877 | NSC87877 代理商
| 购买 56932-43-5 | 56932-43-5 供应商 | 56932-43-5 花费 | 56932-43-5 生产商 | 订购 56932-43-5 | 56932-43-5 代理商