NU6027
目录号: A14136
ATR/CDK 抑制剂
NU6027 是一种强效的细胞ATR活性抑制剂（IC(50)=6.7 μM），并以ATR依赖的方式增强了羟基脲和顺铂的细胞毒性。
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生物活性
| Discription | NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner. | |||||
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产品信息
| 目录号 | A14136 |
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| 分子式 | C11H17N5O2 |
| 分子量 | 251.28 |
| CAS号 | 220036-08-8 |
| SMILES | C1CCC(CC1)COC2=NC(=NC(=C2N=O)N)N |
| 其他名称 | NU-6027, NU 6027 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 47 mg/mL (187.04 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (11.93 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 39.8 mL | 198.98 mL | 397.96 mL |
| 0.5 mM | 7.96 mL | 39.8 mL | 79.59 mL |
| 1 mM | 3.98 mL | 19.9 mL | 39.8 mL |
| 5 mM | 0.8 mL | 3.98 mL | 7.96 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 220036-08-8 | 220036-08-8 供应商 | 220036-08-8 花费 | 220036-08-8 生产商 | 订购 220036-08-8 | 220036-08-8 代理商