NU6027

目录号: A14136

ATR/CDK inhibitor

NU6027 Chemical Structure

CAS NO. 220036-08-8

NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner.

库存: 现货

规格 价格 数量
10 mg
¥ 900.00
25 mg
¥ 2,000.00
50 mg
¥ 3,000.00
10mM * 1mL in DMSO
¥ 820.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner.
Targets
ATR CDK2 DNA-PK CDK1
0.4 μM(Ki)1.3 μM(Ki)2.2 μM(Ki)2.5 μM(Ki)
In vitro DMSO 50 mg/mL (198.98 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (11.93 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 39.8 mL 198.98 mL 397.96 mL
0.5 mM 7.96 mL 39.8 mL 79.59 mL
1 mM 3.98 mL 19.9 mL 39.8 mL
5 mM 0.8 mL 3.98 mL 7.96 mL

*The above data is based on the productmolecular weight 251.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14136
MECHANISM OF ACTION Inhibitor
M. Wt 251.28
Formula C11H17N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 220036-08-8
Synonyms NU-6027, NU 6027
SMILES C1CCC(CC1)COC2=NC(=NC(=C2N=O)N)N

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