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ATR/CDK inhibito

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产品目录号: A14136


产品名 目录号 价格 数量
NU6027 10mg A14136-10
¥ 900.00
NU6027 25mg A14136-25
¥ 2,000.00
NU6027 50mg A14136-50
¥ 3,000.00
NU6027 10mM * 1mL in DMSO A14136-10mM-D
¥ 820.00



NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A14136
Mechanism of action Inhibitor
分子量 251.28
化学分子式 C11H17N5O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 220036-08-8
Synonyms NU-6027, NU 6027
化学名称 6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine


NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner.
0.4 μM(Ki)1.3 μM(Ki)2.2 μM(Ki)2.5 μM(Ki)


Solubility (25°C)* In vitro DMSO 50 mg/mL (198.98 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (11.93 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 39.8 mL 198.98 mL 397.96mL
0.5 mM 7.96 mL 39.8 mL 79.59 mL
1 mM 3.98 mL 19.9 mL 39.8 mL
5 mM 0.8 mL 3.98 mL 7.96 mL

*The above data is based on the productmolecular weight 251.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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