NU7026

目录号: A12752

DNA-PK inhibitor

NU7026 Chemical Structure

CAS NO. 154447-35-5

NU7026 is a novel DNA-dependent protein kinase inhibitor that potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
25 mg
¥ 1,000.00
50 mg
¥ 1,600.00
100 mg
¥ 2,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

NU7026 is a novel DNA-dependent protein kinase inhibitor that potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.
Targets
DNA-PK (Cell-free assay) PI3K (Cell-free assay) ATM (Cell-free assay) ATR (Cell-free assay)
0.23 μM13 μM>100 μM>100 μM
In vitro (25°C) DMSO 1 mg/mL (3.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.55 mL 177.74 mL 355.48 mL
0.5 mM 7.11 mL 35.55 mL 71.1 mL
1 mM 3.55 mL 17.77 mL 35.55 mL
5 mM 0.71 mL 3.55 mL 7.11 mL

*The above data is based on the productmolecular weight 281.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12752
MECHANISM OF ACTION Inhibitor
M. Wt 281.31
Formula C17H15NO3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 154447-35-5
Synonyms NU 7026, NU-7026
SMILES C1COCCN1C2=CC(=O)C3=C(O2)C4=CC=CC=C4C=C3

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