Trusted by 10,000+ Scientists since 2006



Mdm2 拮抗剂

158 Customer Reviews
产品目录号: A10657


产品名 目录号 价格 数量
Nutlin-3 5mg A10657-5
¥ 650.00
Nutlin-3 25mg A10657-25
¥ 2,000.00
Nutlin-3 50mg A10657-50
¥ 3,600.00
Nutlin-3 100mg A10657-100
¥ 5,600.00



MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Nutlin-3 发表的文献 (4)
  • Maxime Parisotto, .et al. PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo, J Exp Med, 2018, Jun 4; 215(6): 1749每1763 PMID: 29743291
  • Ohmuro-Matsuyama Y, .et al. Evaluation of protein-ligand interactions using the luminescent interaction assay FlimPIA with streptavidin-biotin linkage, Anal Biochem, 2018, Dec 15;563:61-66 PMID: 30316750
  • Alisa A. Garaeva, .et al. Mitochondrial dysfunction induces SESN2 gene expression through Activating Transcription Factor 4, Cell Cycle, 2016, 15(1): 64每71 PMID: 26771712
  • A G Evstafieva, .et al. A sustained deficiency of mitochondrial respiratory complex III induces an apoptotic cell death through the p53-mediated inhibition of pro-survival activities of the activating transcription factor 4, Cell Death Dis., 2014, 5(11): e1511. PMID: 25375376

Chemical Information

目录号 A10657
Mechanism of action Antagonist
分子量 581.5
化学分子式 C30H30Cl2N4O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 548472-68-0
Synonyms Nutlin3
SMILES code CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
化学名称 4-(4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one


MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.2 mL 85.98 mL 171.97mL
0.5 mM 3.44 mL 17.2 mL 34.39 mL
1 mM 1.72 mL 8.6 mL 17.2 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 581.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

View Related Products By Research Topics

Cat. No.

Product NameSolubility(mg/mL)
A10255ABT-737<1 mg/mL163 mg/mL<1 mg/mL
A10022ABT-263 (Navitoclax)<1 mg/mL195 mg/mL<1 mg/mL
A10665Obatoclax mesylate (GX15-070)<1 mg/mL83 mg/mL<1 mg/mL
A10955TW-37<1 mg/mL115 mg/mL4 mg/mL
A10984VX-765<1 mg/mL102 mg/mL102 mg/mL
A11090PAC-1<1 mg/mL78 mg/mL16 mg/mL
A10491JNJ 26854165<1 mg/mL66 mg/mL2 mg/mL
A11931RITA (NSC 652287)<1 mg/mL115 mg/mL4 mg/mL
A10522Lenalidomide (CC-5013)<1 mg/mL52 mg/mL<1 mg/mL
A10743Pomalidomide (CC-4047)<1 mg/mL55 mg/mL<1 mg/mL
A11163AT-406<1 mg/mL112 mg/mL112 mg/mL
A11002YM15589 mg/mL55 mg/mL6 mg/mL
A10935Tipifarnib (Zarnestra)<1 mg/mL83 mg/mL<1 mg/mL
A10657Nutlin-3<1 mg/mL116 mg/mL116 mg/mL

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.




Similar product(s)

Keywords:购买 Nutlin-3 | Nutlin-3 供应商 | 订购 Nutlin-3 | Nutlin-3 价格 | Nutlin-3 生产商 | 订单 Nutlin-3 | Nutlin-3 代理商 | 购买 548472-68-0| 548472-68-0 供应商 | 订购 548472-68-0 | 548472-68-0 价格 | 548472-68-0 生产商 | 订单 548472-68-0 | 548472-68-0 代理商|buy Nutlin-3 | Nutlin-3 Supplier | purchase Nutlin-3 | Nutlin-3 cost | Nutlin-3 manufacturer | order Nutlin-3 | Nutlin-3 distributor | buy 548472-68-0| 548472-68-0 Supplier | purchase 548472-68-0 | 548472-68-0 cost | 548472-68-0 manufacturer | order 548472-68-0 | 548472-68-0 distributor