微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
Nutlin 3a是与p53结合的MDM2(小鼠双分钟2)有效抑制剂，可诱导p53调控基因的表达，并在表达功能性p53的细胞中表现出有效的抗增殖活性。
靶点信息
| p53/MDM2 interaction (Cell-free assay) | ||||
| 90 nM |
| In vitro (25°C) | DMSO | 98 mg/mL (168.53 mM) | |
| Water | Insoluble | ||
| Ethanol | 98 mg/mL | ||
| In vivo | 5% DMSO+55% PEG 300+ddH2O | 7 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.2 mL | 85.99 mL | 171.97 mL |
| 0.5 mM | 3.44 mL | 17.2 mL | 34.39 mL |
| 1 mM | 1.72 mL | 8.6 mL | 17.2 mL |
| 5 mM | 0.34 mL | 1.72 mL | 3.44 mL |
*The above data is based on the productmolecular weight 581.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11501 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 581.49 |
| Formula | C30H30Cl2N4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 675576-98-4 |
| Synonyms | Nutlin-3a, (-)-Nutlin-3 |
| SMILES | CC(C)OC1=C(C=CC(=C1)OC)C2=N[C@H]([C@H](N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
p53 and MDM2 proteins-interaction-inhibitor chiral
p53和MDM2蛋白相互作用抑制剂手性是p53和MDM2蛋白之间相互作用的抑制剂。
MI-773 (SAR405838)
MI-773 (SAR405838)是一种新的MDM2-p53相互作用的小分子抑制剂，以高亲和力（Ki = 0.88 nM）结合MDM2，并阻断p53-MDM2…
Lithocholic acid
Lithocholic acid是胆汁酸，用作去污剂以溶解脂肪以供吸收。
Keywords:购买 Nutlin 3a | Nutlin 3a 供应商 | 订购 Nutlin 3a | Nutlin 3a 价格 | Nutlin 3a 生产商 | 订单 Nutlin 3a | Nutlin 3a 代理商 | 购买 675576-98-4| 675576-98-4 供应商 | 订购 675576-98-4 | 675576-98-4 价格 | 675576-98-4 生产商 | 订单 675576-98-4 | 675576-98-4 代理商|buy Nutlin 3a | Nutlin 3a Supplier | purchase Nutlin 3a | Nutlin 3a cost | Nutlin 3a manufacturer | order Nutlin 3a | Nutlin 3a distributor | buy 675576-98-4| 675576-98-4 Supplier | purchase 675576-98-4 | 675576-98-4 cost | 675576-98-4 manufacturer | order 675576-98-4 | 675576-98-4 distributor