NVP-BAW2881

目录号: A12693

VEGFR inhibitor

NVP-BAW2881

NVP-BAW2881 Chemical Structure

CAS NO. 861875-60-7

NVP-BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,800.00
25 mg
¥ 3,400.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

NVP-BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation.
Targets
Target Value
TIE-2
hVEGFR2IC50: 9nM
C-Raf-1IC50: 24nM
B-RAFV599EIC50: 76nM
c-AblIC50: 99nM
mVEGF2IC50: 165nM
RETIC50: 410nM
hVEGFR3IC50: 420nM
hVEGFR1IC50: 820nM
c-KITIC50: 2.5μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.58 mL 117.89 mL 235.79 mL
0.5 mM 4.72 mL 23.58 mL 47.16 mL
1 mM 2.36 mL 11.79 mL 23.58 mL
5 mM 0.47 mL 2.36 mL 4.72 mL

*The above data is based on the productmolecular weight 424.1147. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A12693
MECHANISM OF ACTION Inhibitor
M. Wt 424.1147
Formula C22H15F3N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 861875-60-7
Synonyms BAW2881, BAW-2881, BAW 2881, NVP-BAW-2881, NVP-BAW 2881
SMILES O=C(NC1=CC(C(F)(F)F)=CC=C1)C2=CC=CC3=C2C=CC(OC4=CC=NC(N)=N4)=C3

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