NVP-BSK805

目录号: A11193

JAK 抑制剂

NVP-BSK805

NVP-BSK805 Chemical Structure

CAS NO. 1092499-93-8

NVP-BSK805是喹喔啉JAK2抑制剂对红细胞增多症的有效和选择性抑制,喹喔啉JAK2抑制剂可有效抑制小鼠和大鼠中重组人促红细胞生成素诱导的红细胞增多症和髓外红细胞生成。IC50为0.5 nM,比作用于JAK1, JAK3和TYK2选择性高20倍以上。

库存: 现货

规格 价格 数量
5 mg
¥ 1,400.00
10 mg
¥ 2,000.00
50 mg
¥ 5,800.00
100 mg
¥ 9,200.00
10mM * 1mL in DMSO
¥ 2,170.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

NVP-BSK805是喹喔啉JAK2抑制剂对红细胞增多症的有效和选择性抑制,喹喔啉JAK2抑制剂可有效抑制小鼠和大鼠中重组人促红细胞生成素诱导的红细胞增多症和髓外红细胞生成。IC50为0.5 nM,比作用于JAK1, JAK3和TYK2选择性高20倍以上。
In vitro (25°C) DMSO 113 mg/mL (200.54 mM)
Water 3 mg/mL (5.32 mM)
Ethanol 15 mg/mL (26.62 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.75 mL 88.74 mL 177.47 mL
0.5 mM 3.55 mL 17.75 mL 35.49 mL
1 mM 1.77 mL 8.87 mL 17.75 mL
5 mM 0.35 mL 1.77 mL 3.55 mL

*The above data is based on the productmolecular weight 563.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11193
作用机制 Inhibitor (抑制剂)
M. Wt 563.47
Formula C27H28F2N6O.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1092499-93-8
Synonyms NVPBSK805
SMILES C1CNCCC1N2C=C(C=N2)C3=NC4=C(C=CC=C4N=C3)C5=CC(=C(C(=C5)F)CN6CCOCC6)F.Cl.Cl

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 NVP-BSK805 | NVP-BSK805 供应商 | 订购 NVP-BSK805 | NVP-BSK805 价格 | NVP-BSK805 生产商 | 订单 NVP-BSK805 | NVP-BSK805 代理商 | 购买 1092499-93-8| 1092499-93-8 供应商 | 订购 1092499-93-8 | 1092499-93-8 价格 | 1092499-93-8 生产商 | 订单 1092499-93-8 | 1092499-93-8 代理商|buy NVP-BSK805 | NVP-BSK805 Supplier | purchase NVP-BSK805 | NVP-BSK805 cost | NVP-BSK805 manufacturer | order NVP-BSK805 | NVP-BSK805 distributor | buy 1092499-93-8| 1092499-93-8 Supplier | purchase 1092499-93-8 | 1092499-93-8 cost | 1092499-93-8 manufacturer | order 1092499-93-8 | 1092499-93-8 distributor
Rewards