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MDM2 抑制剂

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产品目录号: A16326


产品名 目录号 价格 数量
NVP-CGM097 5mg A16326-5
¥ 1,000.00
NVP-CGM097 10mg A16326-10
¥ 1,800.00
NVP-CGM097 50mg A16326-50
¥ 5,400.00



NVP-CGM097 is a potent and selective MDM2 inhibitor; an orally bioavailable HDM2 antagonist with potential antineoplastic activity.





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Chemical Information

目录号 A16326
Mechanism of action Inhibitor
分子量 659.26
化学分子式 C38H47ClN4O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1313363-54-0
Synonyms CGM097, CGM 097, CGM-097, NVP CGM097
SMILES code CC(OC(C=C1[C@]2([H])C3=CC=C(Cl)C=C3)=C(OC)C=C1CC(N2C4=CC=C(N(C[C@@]5([H])CC[C@@](N(CC6=O)CCN6C)([H])CC5)C)C=C4)=O)C
化学名称 (S)-1-(4-chlorophenyl)-7-isopropoxy-6-methoxy-2-(4-(methyl(((1r,4S)-4-(4-methyl-3-oxopiperazin-1-yl)cyclohexyl)methyl)amino)phenyl)-1,2-dihydroisoquinolin-3(4H)-one


NVP-CGM097 is a potent and selective MDM2 inhibitor; an orally bioavailable HDM2 antagonist with potential antineoplastic activity.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.17 mL 75.84 mL 151.69mL
0.5 mM 3.03 mL 15.17 mL 30.34 mL
1 mM 1.52 mL 7.58 mL 15.17 mL
5 mM 0.3 mL 1.52 mL 3.03 mL

*The above data is based on the productmolecular weight 659.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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