NVP-TNKS656

Name: NVP-TNKS656
SKU: A15786
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A15786

TNKS2 抑制剂

NVP-TNKS656 是一种高效、选择性强且可口服的 TNKS2 抑制剂，其 IC50 为 6 nM；对 PARP1 和 PARP2 的选择性超过 300 倍。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥525.00	现货
10mg	¥875.00	现货
25mg	¥1,890.00	现货
50mg	¥3,220.00	现货
100mg	¥4,760.00	现货
*10mM 1mL in DMSO**	¥560.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15786
分子式	C27H34N4O5
分子量	494.58
CAS号	1419949-20-4
SMILES	COC1=CC=C(C=C1)C(=O)C2CCN(CC2)CC(=O)N(CC3CC3)CC4=NC(=O)C5=C(N4)CCOC5
其他名称	TNKS656, TNKS-656
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	89 mg/mL (179.95 mM)
	Water	Insoluble
	Ethanol	Warmed: 9 mg/mL (18.19 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.22 mL	101.1 mL	202.19 mL
0.5 mM	4.04 mL	20.22 mL	40.44 mL
1 mM	2.02 mL	10.11 mL	20.22 mL
5 mM	0.4 mL	2.02 mL	4.04 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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