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NVP-TNKS656

TNKS2 抑制剂

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产品目录号: A15786

库存状态:中国现货中国现货

产品名 目录号 价格 数量
NVP-TNKS656 5mg A15786-5
¥ 2,300.00
NVP-TNKS656 10mg A15786-10
¥ 4,000.00
NVP-TNKS656 25mg A15786-25
¥ 6,900.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.

NVP-TNKS656

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Chemical Information

目录号 A15786
Mechanism of action Inhibitor
分子量 494.58
化学分子式 C27H34N4O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1419949-20-4
Synonyms TNKS656, TNKS-656
SMILES code COC1=CC=C(C=C1)C(=O)C2CCN(CC2)CC(=O)N(CC3CC3)CC4=NC(=O)C5=C(N4)CCOC5
化学名称 N-(cyclopropylmethyl)-2-[4-(4-methoxybenzoyl)piperidin-1-yl]-N-[(4-oxo-1,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide

生物活性

Description
NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.
Targets

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.22 mL 101.1 mL 202.19mL
0.5 mM 4.04 mL 20.22 mL 40.44 mL
1 mM 2.02 mL 10.11 mL 20.22 mL
5 mM 0.4 mL 2.02 mL 4.04 mL

*The above data is based on the productmolecular weight 494.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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