O6BTG-octylglucoside
目录号: A11432
MGMT 抑制剂
O6BTG-octylglucoside 是一种强效的 O6-甲基鸟嘌呤-DNA甲基转移酶(MGMT)抑制剂,其 IC50 在体外(细胞提取物)为32纳摩尔,而在HeLa S3细胞中为10纳摩尔。
Discription | O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells. | ||
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目录号 | A11432 |
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分子式 | C24H34BrN5O7S |
分子量 | 616.53 |
CAS号 | 382607-78-5 |
SMILES | [H][C@]1([C@]([H])(O[C@@](OCCCCCCCCN2C3=C(N=C2)C(OCC4=CC(Br)=CS4)=NC(N)=N3)([C@](O)([C@]1(O)[H])[H])[H])CO)O |
其他名称 | Glucose-conjugated MGMT inhibitor |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2