Obeticholic Acid

Name: Obeticholic Acid
SKU: A13866

目录号: A13866

FXR 激动剂

Product Citations (1)

Obeticholic Acid Chemical Structure

CAS NO. 459789-99-2

Obeticholic Acid是一种有效的选择性法呢类X受体（FXR）激动剂，EC50为99 nM。

库存：现货

规格	价格	数量
10 mg	￥ 700.00
50 mg	￥ 1,350.00
10mM * 1mL in DMSO	￥ 550.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

Obeticholic Acid是一种有效的选择性法呢类X受体（FXR）激动剂，EC50为99 nM。

靶点信息

FXR
99 nM(EC50)

溶解度 *

In vitro	DMSO	76 mg/mL (180.68 mM)
	Water	Insoluble
	Ethanol	Warmed: 76 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.77 mL	118.87 mL	237.74 mL
0.5 mM	4.75 mL	23.77 mL	47.55 mL
1 mM	2.38 mL	11.89 mL	23.77 mL
5 mM	0.48 mL	2.38 mL	4.75 mL

*The above data is based on the productmolecular weight 420.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13866
作用机制	Agonist (激动剂)
M. Wt	420.63
Formula	C26H44O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	459789-99-2
Synonyms	INT-747, 6-ECDCA
SMILES	CC[C@@H]1[C@@H]2C[C@@H](CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3[C@@H]1O)CC[C@@H]4[C@H](C)CCC(=O)O)C)C)O