Ocaratuzumab (AME 133v) is an Fc-engineered, humanized IgG1 monoclonal antibody targeting CD20, characterized by a dissociation constant (Kd) of approximately 100 pM. This antibody demonstrates enhanced efficacy in antibody-dependent cell-mediated cytotoxicity (ADCC), making it a potent candidate for research in immune-mediated therapeutic strategies.
Ocaratuzumab (AME 133v) is an Fc-engineered, humanized IgG1 monoclonal antibody targeting CD20, characterized by a dissociation constant (Kd) of approximately 100 pM. This antibody demonstrates enhanced efficacy in antibody-dependent cell-mediated cytotoxicity (ADCC), making it a potent candidate for research in immune-mediated therapeutic strategies.
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