Odanacatib (MK-0822)

目录号: A11265

Cathepsin K Inhibitor

Odanacatib (MK-0822)

Odanacatib (MK-0822) Chemical Structure

CAS NO. 603139-19-1

Odanacatib is an inhibitor of cathepsin K,an enzyme involved in bone resorption.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
25 mg
¥ 2,800.00
50 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 1,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Odanacatib is an inhibitor of cathepsin K,an enzyme involved in bone resorption.
Targets
Cathepsin K (human) Cathepsin K (rabbit)
0.2 nM1 nM
In vitro (25°C) DMSO 100 mg/mL (190.27 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.03 mL 95.13 mL 190.26 mL
0.5 mM 3.81 mL 19.03 mL 38.05 mL
1 mM 1.9 mL 9.51 mL 19.03 mL
5 mM 0.38 mL 1.9 mL 3.81 mL

*The above data is based on the productmolecular weight 525.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11265
MECHANISM OF ACTION Inhibitor
M. Wt 525.6
Formula C25H27F4N3O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 603139-19-1
Synonyms MK0822
SMILES CC(C)(C[C@@H](C(=O)NC1(CC1)C#N)N[C@@H](C2=CC=C(C=C2)C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)F

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