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Darolutamide (ODM-201)

目录号: A15797
Androgen receptor 拮抗剂
ODM-201 是一种针对人类AR(hAR)的强效且完全的拮抗剂,通过在AR-HEK293细胞中的转录激活试验,其IC50值为26 nM。
Grouped product items
规格 价格 库存 数量
1mg
¥280.00
现货
2mg
¥385.00
现货
5mg
¥665.00
现货
10mg
¥1,120.00
现货
25mg
¥1,890.00
现货
50mg
¥2,730.00
现货
100mg
¥4,095.00
现货
500mg
¥8,925.00
现货
10mM * 1mL in DMSO
¥700.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Darolutamide (ODM-201)发表的1篇文献
  • Syeda Afshan, .et al. , Cancer Med, 2024, Sep;13(18):e70240 PMID: 39300962
  • 生物活性
    Discription ODM-201 is a potent and full antagonists for human AR (hAR) with IC50 values of 26 nM by transactivation assays in AR-HEK293 cells.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A15797
    分子式 C19H19ClN6O2
    分子量 398.85
    CAS号 1297538-32-9
    SMILES CC(CN1C=CC(=N1)C2=CC(=C(C=C2)C#N)Cl)NC(=O)C3=NNC(=C3)C(C)O
    其他名称 BAY-1841788
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 74 mg/mL (185.53 mM)
    Water Insoluble
    Ethanol Warmed: 35 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.07 mL 125.36 mL 250.72 mL
    0.5 mM 5.01 mL 25.07 mL 50.14 mL
    1 mM 2.51 mL 12.54 mL 25.07 mL
    5 mM 0.5 mL 2.51 mL 5.01 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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