OG-L002
目录号: A13246
LSD1 抑制剂
OG-L002 是一种强效且特异性的 LSD1 抑制剂,其 IC50 为 20 nM,相较于 MAO-B 和 MAO-A 分别具有 36 倍和 69 倍的选择性。
Discription | OG-L002 is a potent and specific LSD1 inhibitor with IC50 of 20 nM, exhibiting 36- and 69-fold selectivity over MAO-B and MAO-A, respectively. | ||
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目录号 | A13246 |
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分子式 | C15H15NO |
分子量 | 225.28 |
CAS号 | 1357302-64-7 |
SMILES | C1[C@@H]([C@H]1N)C2=CC=C(C=C2)C3=CC(=CC=C3)O |
其他名称 | OGL002, OG L002 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 41 mg/mL (181.99 mM) | |
Water | Insoluble | ||
Ethanol | 17 mg/mL (75.45 mM) | ||
In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80 | 19 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 44.39 mL | 221.95 mL | 443.89 mL |
0.5 mM | 8.88 mL | 44.39 mL | 88.78 mL |
1 mM | 4.44 mL | 22.19 mL | 44.39 mL |
5 mM | 0.89 mL | 4.44 mL | 8.88 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2