Ogalvibart (C-135-LS) is a human monoclonal antibody of the IgG1 subtype, specifically designed to target the SARS-CoV-2 virus. It exhibits high affinity binding to the receptor-binding domain (RBD) of the spike (S) glycoprotein on the virus surface. When used in conjunction with C144LS at a 1:1 ratio, Ogalvibart demonstrates significant preventive efficacy, effectively inhibiting the progression of COVID-19 in a rhesus monkey model. This antibody is pivotal for research focused on the mechanisms of SARS-CoV-2 infection and the development of therapeutic strategies.
Ogalvibart (C-135-LS) is a human monoclonal antibody of the IgG1 subtype, specifically designed to target the SARS-CoV-2 virus. It exhibits high affinity binding to the receptor-binding domain (RBD) of the spike (S) glycoprotein on the virus surface. When used in conjunction with C144LS at a 1:1 ratio, Ogalvibart demonstrates significant preventive efficacy, effectively inhibiting the progression of COVID-19 in a rhesus monkey model. This antibody is pivotal for research focused on the mechanisms of SARS-CoV-2 infection and the development of therapeutic strategies.
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