Oleclumab (MEDI9447) is a human IgG1?? monoclonal antibody designed to selectively target and inhibit the exonuclease activity of CD73, an extracellular enzyme. By modulating the activity of CD73, Oleclumab influences the composition of bone marrow and lymphoid infiltrating leukocyte populations within the tumor microenvironment, demonstrating significant anti-tumor activity. This antibody is pivotal in studies focused on tumor immunology and the development of cancer immunotherapies.
Oleclumab (MEDI9447) is a human IgG1?? monoclonal antibody designed to selectively target and inhibit the exonuclease activity of CD73, an extracellular enzyme. By modulating the activity of CD73, Oleclumab influences the composition of bone marrow and lymphoid infiltrating leukocyte populations within the tumor microenvironment, demonstrating significant anti-tumor activity. This antibody is pivotal in studies focused on tumor immunology and the development of cancer immunotherapies.
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