Olendalizumab (ALXN1007) is a humanized monoclonal antibody derived from mouse IgG2-G4-??, specifically designed to target Complement protein C5a with a dissociation constant (Ki) of 60 pM. This antibody plays a crucial role in modulating the complement inflammatory pathway. Olendalizumab is primarily utilized in research focused on complement-mediated disorders, particularly those associated with coronavirus infections. This specificity and application make it a valuable tool for studies aimed at understanding and potentially mitigating the impact of complement system dysregulation in viral diseases.
Olendalizumab (ALXN1007) is a humanized monoclonal antibody derived from mouse IgG2-G4-??, specifically designed to target Complement protein C5a with a dissociation constant (Ki) of 60 pM. This antibody plays a crucial role in modulating the complement inflammatory pathway. Olendalizumab is primarily utilized in research focused on complement-mediated disorders, particularly those associated with coronavirus infections. This specificity and application make it a valuable tool for studies aimed at understanding and potentially mitigating the impact of complement system dysregulation in viral diseases.
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