Oltipraz
目录号: A13164
Nrf2 activator
Oltipraz 抑制 HIF-1alpha 活性和依赖 HIF-1alpha 的肿瘤生长,这可能是由于通过 S6K1 抑制降低 HIF-1alpha 稳定性,结合 H2O2 清除效应所致。
Discription | Oltipraz inhibits HIF-1alpha activity and HIF-1alpha-dependent tumor growth, which may result from a decrease in HIF-1alpha stability through S6K1 inhibition in combination with an H2O2-scavenging effect. | ||
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Targets |
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目录号 | A13164 |
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分子式 | C8H6N2S3 |
分子量 | 226.34 |
CAS号 | 64224-21-1 |
SMILES | CC1=C(SSC1=S)C2=NC=CN=C2 |
其他名称 | RP 35972, NSC 347901 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 34 mg/mL (150.21 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 44.18 mL | 220.91 mL | 441.81 mL |
0.5 mM | 8.84 mL | 44.18 mL | 88.36 mL |
1 mM | 4.42 mL | 22.09 mL | 44.18 mL |
5 mM | 0.88 mL | 4.42 mL | 8.84 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2