Olutasidenib (FT-2102)
目录号: A18789
IDH1 抑制剂
Olutasidenib 是一种针对突变型异柠檬酸脱氢酶(IDH)1的强效、选择性抑制剂,用于治疗急性髓系白血病。
| Discription | Olutasidenib is a potent, selective inhibitor of mutant Isocitrate dehydrogenase (IDH)1 for the treatment of acute myeloid leukemia. |
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| 目录号 | A18789 |
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| 分子式 | C18H15ClN4O2 |
| 分子量 | 354.79 |
| CAS号 | 1887014-12-1 |
| SMILES | N#CC1=CC=C(N[C@H](C2=CC3=C(NC2=O)C=CC(Cl)=C3)C)C(N1C)=O |
| 其他名称 | Olutasidenib; FT-2102; FT 2102; FT2102; |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 70 mg/mL (197.29 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.19 mL | 140.93 mL | 281.86 mL |
| 0.5 mM | 5.64 mL | 28.19 mL | 56.37 mL |
| 1 mM | 2.82 mL | 14.09 mL | 28.19 mL |
| 5 mM | 0.56 mL | 2.82 mL | 5.64 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2