ON 146040

目录号: A16266

dual PI3K and BCR-ABL 抑制剂

ON 146040

ON 146040 Chemical Structure

CAS NO. 1404231-34-0

ON 146040是第一个靶向STAT3和STAT5途径的PI3K和BCR-ABL双重抑制剂;抑制PI3Kα/δ同工型,IC50为14/20 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 3,200.00
10 mg
¥ 4,800.00
50 mg
¥ 14,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

ON 146040是第一个靶向STAT3和STAT5途径的PI3K和BCR-ABL双重抑制剂;抑制PI3Kα/δ同工型,IC50为14/20 nM。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.43 mL 102.13 mL 204.27 mL
0.5 mM 4.09 mL 20.43 mL 40.85 mL
1 mM 2.04 mL 10.21 mL 20.43 mL
5 mM 0.41 mL 2.04 mL 4.09 mL

*The above data is based on the productmolecular weight 489.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16266
作用机制 Inhibitor (抑制剂)
M. Wt 489.55
Formula C24H23N7O3S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1404231-34-0
Synonyms ON-146040, ON146040
SMILES O=C(NC(C=NC(NC1=CC=C(N2CCN(C)CC2)C=C1)=N3)=C3S/4)C4=C\C5=CC=C([N+]([O-])=O)C=C5

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