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ON123300

CDK4 抑制剂?€?

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产品目录号: A12584

库存状态:中国现货中国现货

产品名 目录号 价格 数量
ON123300 5mg A12584-5
¥ 1,200.00
ON123300 10mg A12584-10
¥ 1,800.00
ON123300 25mg A12584-25
¥ 4,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

ON123300 is a potent multikinase inhibitor and may be potential useful for brain tumor chemotherapy. ON123300 strongly inhibits Ark5 and CDK4, as well as growth factor receptor tyrosine kinases such as ??-type platelet-derived growth factor receptor (PDGFR??).

ON123300

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Chemical Information

目录号 A12584
Mechanism of action Inhibitor
分子量 429.23
化学分子式 C24H27N7O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1357470-29-1
Synonyms ON123300, ON 123300
SMILES code N#CC1=CC2=CN=C(NC3=CC=C(N4CCN(C)CC4)C=C3)N=C2N(C5CCCC5)C1=O
化学名称 8-cyclopentyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carbonitrile

生物活性

Description
ON123300 is a potent multikinase inhibitor and may be potential useful for brain tumor chemotherapy. ON123300 strongly inhibits Ark5 and CDK4, as well as growth factor receptor tyrosine kinases such as ??-type platelet-derived growth factor receptor (PDGFR??).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.3 mL 116.49 mL 232.98mL
0.5 mM 4.66 mL 23.3 mL 46.6 mL
1 mM 2.33 mL 11.65 mL 23.3 mL
5 mM 0.47 mL 2.33 mL 4.66 mL

*The above data is based on the productmolecular weight 429.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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