ON123300
目录号: A12584
CDK4 抑制剂?€?
ON123300 是一种强效的多激酶抑制剂,可能对脑瘤化疗具有潜在的效用。ON123300 强烈抑制 Ark5 和 CDK4,以及如 PDGFRβ 类的生长因子受体酪氨酸激酶。
| Discription | ON123300 is a potent multikinase inhibitor and may be potential useful for brain tumor chemotherapy. ON123300 strongly inhibits Ark5 and CDK4, as well as growth factor receptor tyrosine kinases such as ??-type platelet-derived growth factor receptor (PDGFR??). | |||||
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| Cell Research |
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| 目录号 | A12584 |
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| 分子式 | C24H27N7O |
| 分子量 | 429.23 |
| CAS号 | 1357470-29-1 |
| SMILES | N#CC1=CC2=CN=C(NC3=CC=C(N4CCN(C)CC4)C=C3)N=C2N(C5CCCC5)C1=O |
| 其他名称 | ON123300, ON 123300 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 26 mg/mL (60.53 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.3 mL | 116.49 mL | 232.98 mL |
| 0.5 mM | 4.66 mL | 23.3 mL | 46.6 mL |
| 1 mM | 2.33 mL | 11.65 mL | 23.3 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2