ONX-0914

Name: ONX-0914
SKU: A12653
Price: 280 CNY
Rating: 5 (5 reviews)

目录号: A12653

Immunoproteasome 抑制剂

5 篇发表文献

ONX 0914 是一种免疫蛋白酶体抑制剂，具有潜在的治疗应用于自身免疫性疾病，如类风湿性关节炎、炎症性肠病和红斑狼疮。ONX 0914 被设计为一种强效的免疫蛋白酶体抑制剂，对构成型蛋白酶体的交叉反应性最小。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
1mg	¥280.00	现货
5mg	¥805.00	现货
10mg	¥1,330.00	现货
25mg	¥2,240.00	现货
50mg	¥3,360.00	现货
100mg	¥6,440.00	现货
*10mM 1mL in DMSO**	¥945.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用ONX-0914发表的5篇文献

David J Zahavi, .et al. , Cancer Biol Ther, 2023, Dec 31;24(1):2269637 PMID: 37878417

Yuki Sasaki, .et al. , JCI Insight, 2022, Apr 8;7(7) PMID: 35393946

Ming-Shu Mo, .et al. , Transl Neurodegener, 2018, 7: 19 PMID: 30128145

Ohkusu-Tsukada K, .et al. , Int Arch Allergy Immunol, 2018, 176(2):91-100 PMID: 29669333

Arimochi H, .et al. , Sci Rep, 2016, May 26;6:26791 PMID: 27225296

生物活性

Discription

ONX 0914 is an immunoproteasome inhibitor with potential treatment applications in autoimmune disorders, such as rheumatoid arthritis, inflammatory bowel disease and lupus. ONX 0914 was designed to be a potent inhibitor of the immunoproteasome with minimal cross-reactivity for the constitutive proteasome.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12653
分子式	C31H40N4O7
分子量	580.67
CAS号	960374-59-8
SMILES	C[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)OC)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)[C@]3(CO3)C)NC(=O)CN4CCOCC4
其他名称	ONX0914, ONX 0914, PR-957
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	87 mg/mL (149.82 mM)
	Water	Insoluble
	Ethanol	87 mg/mL (149.82 mM)
In vivo	2% DMSO+castor oil	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.22 mL	86.11 mL	172.21 mL
0.5 mM	3.44 mL	17.22 mL	34.44 mL
1 mM	1.72 mL	8.61 mL	17.22 mL
5 mM	0.34 mL	1.72 mL	3.44 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 ONX-0914 | ONX-0914 供应商 | ONX-0914 花费 | ONX-0914 生产商 | 订购 ONX-0914 | ONX-0914 代理商 | 购买 960374-59-8 | 960374-59-8 供应商 | 960374-59-8 花费 | 960374-59-8 生产商 | 订购 960374-59-8 | 960374-59-8 代理商