Ordesekimab is a fully human IgG1κ monoclonal antibody that targets interleukin-15 (IL-15). It blocks the interaction of IL-15 with the IL-2Rβ and common γ chain components of the IL-15 receptor complex, without affecting binding to IL-15Rα. Ordesekimab is a valuable tool for studying IL-15–driven immune responses and is under investigation for use in nonresponsive celiac disease (NRCD).
Ordesekimab is a fully human IgG1κ monoclonal antibody that targets interleukin-15 (IL-15). It blocks the interaction of IL-15 with the IL-2Rβ and common γ chain components of the IL-15 receptor complex, without affecting binding to IL-15Rα. Ordesekimab is a valuable tool for studying IL-15–driven immune responses and is under investigation for use in nonresponsive celiac disease (NRCD).
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