Iadademstat (ORY-1001, RG-6016)

Name: Iadademstat (ORY-1001, RG-6016)
SKU: A15893
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A15893

LSD1 抑制剂

ORY-1001 是一种口服活性的、选择性的赖氨酸特异性去甲基酶 LSD1/KDM1A 抑制剂，其 IC50 值小于 20 nM，对相关的 FAD 依赖性氨氧化酶具有高度选择性。目前处于第一阶段临床试验。

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Grouped product items
规格	价格	库存
1mg	¥315.00	现货
2mg	¥490.00	现货
5mg	¥630.00	现货
10mg	¥1,120.00	现货
25mg	¥2,240.00	现货
50mg	¥4,060.00	现货
100mg	¥6,860.00	现货
500mg	¥13,825.00	现货
*10mM 1mL in DMSO**	¥910.00	现货
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Data Sheet

SDS

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生物活性

Discription

ORY-1001 is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor with IC50 of <20 nM, with high selectivity against related FAD dependent aminoxidases. Phase 1.

Targets

Target	Value

产品信息

目录号	A15893
分子式	C15H22N2.2HCl
分子量	303.27
CAS号	1431326-61-2
SMILES	NC1CCC(N[C@@H]2C[C@H]2C3=CC=CC=C3)CC1.Cl.Cl
其他名称	RG6016, RG-6016
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	4 mg/mL (13.18 mM)
	Water	53 mg/mL (174.76 mM)
	Ethanol	Warmed: 3 mg/mL (9.89 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.97 mL	164.87 mL	329.74 mL
0.5 mM	6.59 mL	32.97 mL	65.95 mL
1 mM	3.3 mL	16.49 mL	32.97 mL
5 mM	0.66 mL	3.3 mL	6.59 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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