Osemitamab is a monoclonal antibody targeting claudin-18.2, expressed in Chinese Hamster Ovary (CHO) cells engineered with a knockout of the fucosyltransferase 8 gene (FUT8). The absence of FUT8 results in a fucose-deficient antibody, significantly enhancing its Antibody-Dependent Cellular Cytotoxicity (ADCC) capabilities. This product is utilized effectively in combination with Capecitabine and Oxaliplatin for research into gastric (G) and gastroesophageal junction (GEJ) cancers.
Osemitamab is a monoclonal antibody targeting claudin-18.2, expressed in Chinese Hamster Ovary (CHO) cells engineered with a knockout of the fucosyltransferase 8 gene (FUT8). The absence of FUT8 results in a fucose-deficient antibody, significantly enhancing its Antibody-Dependent Cellular Cytotoxicity (ADCC) capabilities. This product is utilized effectively in combination with Capecitabine and Oxaliplatin for research into gastric (G) and gastroesophageal junction (GEJ) cancers.
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