OSI-420

目录号: A10678

EGFR Inhibitor

OSI-420 Chemical Structure

CAS NO. 183320-51-6

OSI-420 (Desmethyl Erlotinib,CP-473420) is an orally active EGFR tyrosin kinase inhibitor, which inhibits receptor tyrosine kinases (TKs) by inhibition of the intercellular domain .

库存: 现货

规格 价格 数量
5 mg
¥ 1,100.00
10 mg
¥ 2,000.00
50 mg
¥ 5,200.00
100 mg
¥ 9,200.00
10mM * 1mL in DMSO
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

OSI-420 (Desmethyl Erlotinib,CP-473420) is an orally active EGFR tyrosin kinase inhibitor, which inhibits receptor tyrosine kinases (TKs) by inhibition of the intercellular domain .
靶点信息
EGFR
2 nM
In vitro DMSO 83 mg/mL heating (199.58 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.04 mL 120.22 mL 240.44 mL
0.5 mM 4.81 mL 24.04 mL 48.09 mL
1 mM 2.4 mL 12.02 mL 24.04 mL
5 mM 0.48 mL 2.4 mL 4.81 mL

*The above data is based on the productmolecular weight 415.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10678
MECHANISM OF ACTION Inhibitor
M. Wt 415.9
Formula C21H21N3O4.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 183320-51-6
Synonyms Desmethyl Erlotinib,CP-473420, OSI420
SMILES COCCOC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCO.Cl

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