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OSU-03012

促销

PDK-1 抑制剂

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产品目录号: A10681

库存状态:中国现货中国现货

产品名 目录号 价格 数量
OSU-03012 5mg A10681-5
¥ 500.00
OSU-03012 25mg A10681-25
¥ 1,600.00
OSU-03012 50mg A10681-50
¥ 3,000.00
OSU-03012 100mg A10681-100
¥ 4,700.00
OSU-03012 10mM * 1mL in DMSO A10681-10mM-D
¥ 900.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

OSU-03012 is a novel celecoxib derivative, without cyclooxygenase-2 inhibitory activity, capable of inducing apoptosis in various cancer cells types.

OSU-03012

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Chemical Information

目录号 A10681
Mechanism of action Inhibitor
分子量 460.2
化学分子式 C26H19F3N4O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 742112-33-0
Synonyms N/AAR-12, OSU03012
SMILES code C1=CC=C2C(=C1)C=CC3=C2C=CC(=C3)C4=CC(=NN4C5=CC=C(C=C5)NC(=O)CN)C(F)(F)F
化学名称 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide

生物活性

Description
OSU-03012 is a novel celecoxib derivative, without cyclooxygenase-2 inhibitory activity, capable of inducing apoptosis in various cancer cells types.
Targets
PDK-1 (Cell-free assay)
5 μM

溶解性

Solubility (25°C) * In vitro DMSO 11 mg/mL (23.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.73 mL 108.65 mL 217.3mL
0.5 mM 4.35 mL 21.73 mL 43.46 mL
1 mM 2.17 mL 10.86 mL 21.73 mL
5 mM 0.43 mL 2.17 mL 4.35 mL

*The above data is based on the productmolecular weight 460.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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