OSU-03012

目录号: A10681

PDK-1 inhibitor

OSU-03012 Chemical Structure

CAS NO. 742112-33-0

OSU-03012 is a novel celecoxib derivative, without cyclooxygenase-2 inhibitory activity, capable of inducing apoptosis in various cancer cells types.

库存: 现货

规格 价格 数量
5 mg
¥ 500.00
25 mg
¥ 1,600.00
50 mg
¥ 3,000.00
100 mg
¥ 4,700.00
10mM * 1mL in DMSO
¥ 900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

OSU-03012 is a novel celecoxib derivative, without cyclooxygenase-2 inhibitory activity, capable of inducing apoptosis in various cancer cells types.
Targets
PDK-1 (Cell-free assay)
5 μM
In vitro (25°C) DMSO 11 mg/mL (23.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.73 mL 108.65 mL 217.3 mL
0.5 mM 4.35 mL 21.73 mL 43.46 mL
1 mM 2.17 mL 10.86 mL 21.73 mL
5 mM 0.43 mL 2.17 mL 4.35 mL

*The above data is based on the productmolecular weight 460.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10681
MECHANISM OF ACTION Inhibitor
M. Wt 460.2
Formula C26H19F3N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 742112-33-0
Synonyms N/AAR-12, OSU03012
SMILES C1=CC=C2C(=C1)C=CC3=C2C=CC(=C3)C4=CC(=NN4C5=CC=C(C=C5)NC(=O)CN)C(F)(F)F

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