OSU-T315
目录号: A20870
ILK 抑制剂
OSU-T315（ILK-IN-1）是一种小分子整合素连接激酶（ILK）抑制剂，其IC50为0.6 μM，通过去磷酸化AKT-Ser473及其他ILK靶点（GSK-3β和肌球蛋白轻链）来抑制PI3K/AKT信号通路。
顾客使用 Adooq 产品发表的高质量科研文献
生物活性
| Discription | OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain). |
|---|
产品信息
| 目录号 | A20870 |
|---|---|
| 分子式 | C30H30F3N5O |
| 分子量 | 533.59 |
| CAS号 | 2070015-22-2 |
| SMILES | O=C(NC)CCC1=CC(C2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)=NN1C4=CC=C(N5CCNCC5)C=C4 |
| 其他名称 | OSUT315, OSU T315 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 91 mg/mL (170.53 mM) | |
| Water | <1 mg/mL | ||
| Ethanol | 10 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.74 mL | 93.7 mL | 187.41 mL |
| 0.5 mM | 3.75 mL | 18.74 mL | 37.48 mL |
| 1 mM | 1.87 mL | 9.37 mL | 18.74 mL |
| 5 mM | 0.37 mL | 1.87 mL | 3.75 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 OSU-T315 | OSU-T315 供应商 | OSU-T315 花费 | OSU-T315 生产商 | 订购 OSU-T315 | OSU-T315 代理商
| 购买 2070015-22-2 | 2070015-22-2 供应商 | 2070015-22-2 花费 | 2070015-22-2 生产商 | 订购 2070015-22-2 | 2070015-22-2 代理商