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Chemical Information
| 目录号 | A16023 |
|---|---|
| Mechanism of action | Inhibitor |
| 分子量 | 350.43 |
| 化学分子式 | C20H18N2O2S |
| Solubility | DMSO |
| 纯度 | >98% |
| 储存方式 | at -20°C 2 years |
| CAS No. | 1338540-55-8 |
| Synonyms | OTS 514, OTS-514 |
| SMILES code | NC[C@H](C)C1=CC=C(C2=C(O)C=CC3=C2C(C=CS4)=C4C(N3)=O)C=C1 |
| 化学名称 | (R)-9-(4-(1-aminopropan-2-yl)phenyl)-8-hydroxythieno[2,3-c]quinolin-4(5H)-one |
Description |
OTS514, a thieno[2,3-c]quinolone compound, is a highly potent TOPK inhibitor with an IC50 value of 2.6 nM. The compound can inhibit TOPK kinase activity. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.54 mL | 142.68 mL | 285.36mL |
| 0.5 mM | 5.71 mL | 28.54 mL | 57.07 mL |
| 1 mM | 2.85 mL | 14.27 mL | 28.54 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.71 mL |
*The above data is based on the productmolecular weight 350.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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