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OTS514, a thieno[2,3-c]quinolone compound, is a highly potent TOPK inhibitor with an IC50 value of 2.6 nM. The compound can inhibit TOPK kinase activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.54 mL | 142.68 mL | 285.36 mL |
| 0.5 mM | 5.71 mL | 28.54 mL | 57.07 mL |
| 1 mM | 2.85 mL | 14.27 mL | 28.54 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.71 mL |
*The above data is based on the productmolecular weight 350.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16023 |
|---|---|
| MECHANISM OF ACTION | Inhibitor |
| M. Wt | 350.43 |
| Formula | C20H18N2O2S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1338540-55-8 |
| Synonyms | OTS 514, OTS-514 |
| SMILES | NC[C@H](C)C1=CC=C(C2=C(O)C=CC3=C2C(C=CS4)=C4C(N3)=O)C=C1 |
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