P 22077
目录号: A12933
USP7 抑制剂
P 22077 是一种能够渗透细胞的抑制剂,针对泛素特异性蛋白酶(IC50 = 8.6 μM)以及与之密切相关的去泛素化酶(DUB)USP47。
Discription | P 22077 is a cell-permeable inhibitor of the ubiquitin-specific protease (IC?? = 8.6 μM) and the closely related deubiquitinase (DUB) USP47. | |||||
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Targets |
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Cell Research |
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目录号 | A12933 |
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分子式 | C12H7F2NO3S2 |
分子量 | 315.32 |
CAS号 | 1247819-59-5 |
SMILES | CC(=O)C1=CC(=C(S1)SC2=C(C=C(C=C2)F)F)[N+](=O)[O-] |
其他名称 | P22077 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 57 mg/mL (180.76 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 2 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 31.71 mL | 158.57 mL | 317.14 mL |
0.5 mM | 6.34 mL | 31.71 mL | 63.43 mL |
1 mM | 3.17 mL | 15.86 mL | 31.71 mL |
5 mM | 0.63 mL | 3.17 mL | 6.34 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2