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PA-824 (Pretomanid)

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产品目录号: A11401

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PA-824 5mg A11401-5
¥ 600.00
PA-824 10mg A11401-10
¥ 900.00
PA-824 50mg A11401-50
¥ 2,000.00
PA-824 100mg A11401-100
¥ 3,000.00
PA-824 10mM * 1mL in DMSO A11401-10mM-D
¥ 900.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PA-824 is an experimental anti-tuberculosis drug.

PA-824 (Pretomanid)

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 PA-824 (Pretomanid) 发表的文献 (1)
  • Alexandre L車pez-Gav赤n, .et al. In vitro activity against Mycobacterium tuberculosis of levofloxacin, moxifloxacin and UB-8902 in combination with clofazimine and pretomanid., Int J Antimicrob Agents., 2015, Nov;46(5):582-5 PMID: 26421981

Chemical Information

目录号 A11401
Mechanism of action
分子量 359.3
化学分子式 C14H12F3N3O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 187235-37-6
Synonyms PA824
SMILES code C1[C@@H](COC2=NC(=CN21)[N+](=O)[O-])OCC3=CC=C(C=C3)OC(F)(F)F
化学名称 (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine

生物活性

Description
PA-824 is an experimental anti-tuberculosis drug.
Targets
tuberculosis

溶解性

Solubility (25°C) * In vitro DMSO 72 mg/mL (200.41 mM)
Water <1 mg/mL (<1 mM)
Ethanol 16 mg/mL (44.53 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.83 mL 139.16 mL 278.32mL
0.5 mM 5.57 mL 27.83 mL 55.66 mL
1 mM 2.78 mL 13.92 mL 27.83 mL
5 mM 0.56 mL 2.78 mL 5.57 mL

*The above data is based on the productmolecular weight 359.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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