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Caspase activator

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产品目录号: A11090


产品名 目录号 价格 数量
PAC-1 10mg A11090-10
¥ 400.00
PAC-1 50mg A11090-50
¥ 1,400.00
PAC-1 100mg A11090-100
¥ 2,500.00
PAC-1 200mg A11090-200
¥ 4,500.00
PAC-1 10mM * 1mL in DMSO A11090-10mM-D
¥ 500.00



PAC-1 is first procaspase activating compound.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 PAC-1 发表的文献 (1)
  • Hirosumi Tamura, .et al. Evaluation of anticancer agents using patient-derived tumor organoids characteristically similar to source tissues, Oncol Rep, 2018, Aug; 40(2): 635每646 PMID: 29917168

Chemical Information

目录号 A11090
Mechanism of action Activator
分子量 392.5
化学分子式 C23H28N4O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 315183-21-2
Synonyms PAC1,first procaspase activating compound
化学名称 4-(Phenylmethyl)-1-piperazineaceticacid [[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide


PAC-1 is first procaspase activating compound.
0.22 μM(EC50)


Solubility (25°C) * In vitro DMSO 78 mg/mL (198.73 mM)
Water <1 mg/mL (<1 mM)
Ethanol 16 mg/mL (40.76 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.48 mL 127.39 mL 254.78mL
0.5 mM 5.1 mL 25.48 mL 50.96 mL
1 mM 2.55 mL 12.74 mL 25.48 mL
5 mM 0.51 mL 2.55 mL 5.1 mL

*The above data is based on the productmolecular weight 392.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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