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Paclitaxel (Taxol)

促销

Microtubule Associated 抑制剂

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产品目录号: A10689

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Paclitaxel (Taxol) 10mg A10689-10
¥ 300.00
Paclitaxel (Taxol) 50mg A10689-50
¥ 500.00
Paclitaxel (Taxol) 100mg A10689-100
¥ 800.00
Paclitaxel (Taxol) 200mg A10689-200
¥ 1,000.00
Paclitaxel (Taxol) 10mM * 1mL in DMSO A10689-10mM-D
¥ 500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Paclitaxel (Taxol) is a mitotic inhibitor that stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division.

Paclitaxel (Taxol)

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Paclitaxel (Taxol) 发表的文献 (2)
  • Owiti AO, .et al. PSMA Antibody-Conjugated Pentablock Copolymer Nanomicellar Formulation for Targeted Delivery to Prostate Cancer, AAPS PharmSciTech, 2018, Nov;19(8):3534-3549 PMID: 30151731
  • Owiti AO, .et al. Strategic Pentablock Copolymer Nanomicellar Formulation for Paclitaxel Delivery System, AAPS PharmSciTech, 2018, Oct;19(7):3110-3122 PMID: 30112614

Chemical Information

目录号 A10689
Mechanism of action Inhibitor
分子量 853.9
化学分子式 C47H51NO14
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 33069-62-4
Synonyms Taxol
SMILES code CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
化学名称 (2α,4α,5β,7β,10β,13α)-4,10-bis(acetyloxy)-13-{[(2R,3S)- 3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}- 1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate

生物活性

Description
Paclitaxel (Taxol) is a mitotic inhibitor that stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division.
Targets
Microtubule (human endothelial cells)
0.1 pM

溶解性

Solubility (25°C) * In vitro DMSO 171 mg/mL (200.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol 18 mg/mL (21.07 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.71 mL 58.55 mL 117.11mL
0.5 mM 2.34 mL 11.71 mL 23.42 mL
1 mM 1.17 mL 5.86 mL 11.71 mL
5 mM 0.23 mL 1.17 mL 2.34 mL

*The above data is based on the productmolecular weight 853.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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