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Palomid 529 (P529)

促销

AKT 抑制剂

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产品目录号: A10693

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Palomid 529 10mg A10693-10
¥ 1,000.00
Palomid 529 50mg A10693-50
¥ 4,200.00
Palomid 529 100mg A10693-100
¥ 7,500.00
Palomid 529 200mg A10693-200
¥ 12,800.00
Palomid 529 (P529) 10mM * 1mL in DMSO A10693-10mM-D
¥ 1,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Palomid 529 is a dual TORC1/2 inhibitor of the PI3K/Akt/mTOR pathway having broad activity in angiogenesis and cellular proliferation.

Palomid 529 (P529)

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Chemical Information

目录号 A10693
Mechanism of action Inhibitor
分子量 406.4
化学分子式 C24H22O6
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 914913-88-5
Synonyms P529
SMILES code CC(C1=CC2=C(C=C1)C3=CC(=C(C=C3OC2=O)OCC4=CC=C(C=C4)OC)OC)O
化学名称 3-(4-methoxybenzyloxy)-8-(1-hydroxyethyl)-2-methoxy-6H-benzo[c]chromen-6-one

生物活性

Description
Palomid 529 is a dual TORC1/2 inhibitor of the PI3K/Akt/mTOR pathway having broad activity in angiogenesis and cellular proliferation.
Targets
mTORC1 mTORC2

溶解性

Solubility (25°C)* In vitro DMSO 81 mg/mL (199.29 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.61 mL 123.03 mL 246.06mL
0.5 mM 4.92 mL 24.61 mL 49.21 mL
1 mM 2.46 mL 12.3 mL 24.61 mL
5 mM 0.49 mL 2.46 mL 4.92 mL

*The above data is based on the productmolecular weight 406.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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