Paprotrain
目录号: A20346
MKLP-2 抑制剂
Paprotrain 是一种能够渗透细胞的抑制剂,专门针对kinesin MKLP-2。它能够抑制 MKLP-2 的 ATPase 活性,具有 1.35 μM 的 IC50 和 3.36 μM 的 Ki,并对 DYRK1A 显示出中等的抑制活性,IC50 为 5.5 μM。
| Discription | Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM. | |||||
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| 目录号 | A20346 |
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| 分子式 | C16H11N3 |
| 分子量 | 245.28 |
| CAS号 | 57046-73-8 |
| SMILES | N#C/C(C1=CNC2=CC=CC=C21)=C\C3=CN=CC=C3 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2