Parbendazole
目录号: A18981
Microtubule assembly 抑制剂
Parbendazole 是一种强效的微管组装抑制剂,能够破坏微管蛋白,其半抑制浓度(EC50)为8.79纳摩尔,并显示出广谱的驱虫活性。
| Discription | Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 8.79?nM, and exhibits a broad-spectrum anthelmintic activity. | |||||
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| Cell Research |
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| 目录号 | A18981 |
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| 分子式 | C13H17N3O2 |
| 分子量 | 247.29 |
| CAS号 | 14255-87-9 |
| SMILES | O=C(OC)NC1=NC2=CC=C(CCCC)C=C2N1 |
| 其他名称 | SKF 29044, SKF29044, SKF-29044 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 3 mg/mL (12.13 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.44 mL | 202.19 mL | 404.38 mL |
| 0.5 mM | 8.09 mL | 40.44 mL | 80.88 mL |
| 1 mM | 4.04 mL | 20.22 mL | 40.44 mL |
| 5 mM | 0.81 mL | 4.04 mL | 8.09 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2