Parsaclisib
目录号: A13561
PI3Kδ 抑制剂
Parsaclisib 是一种强效且选择性的 PI3Kδ 抑制剂,在 1 mM ATP 的条件下,其 IC50 为 1 nM,并且对 PI3Kα、PI3Kβ、PI3Kγ 以及其他 57 种激酶显示出约 20,000 倍的选择性。
Discription | Parsaclisib is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP, and shows appr 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases. | |||||
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Cell Research |
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目录号 | A13561 |
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分子式 | C20H22ClFN6O2 |
分子量 | 432.88 |
CAS号 | 1426698-88-5 |
SMILES | CCOC1=C([C@@H](C2)CNC2=O)C(F)=C(Cl)C=C1[C@@H](N3C4=NC=NC(N)=C4C(C)=N3)C |
其他名称 | INCB050465, INCB-050465, INCB 050465 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2