Parsatuzumab (Anti-EGFL7; RG 7414) is a humanized monoclonal antibody designed to function as an immunomodulator by targeting and binding to the epidermal growth factor-like domain 7 (EGFL7). This antibody selectively inhibits the interaction between EGFL7 and endothelial cells, which may impede vascular regrowth and modulate the effects of vascular endothelial growth factor (VEGF) inhibition. Parsatuzumab is primarily researched for its potential applications in the regulation of angiogenesis and tumor microenvironment modulation.
Parsatuzumab (Anti-EGFL7; RG 7414) is a humanized monoclonal antibody designed to function as an immunomodulator by targeting and binding to the epidermal growth factor-like domain 7 (EGFL7). This antibody selectively inhibits the interaction between EGFL7 and endothelial cells, which may impede vascular regrowth and modulate the effects of vascular endothelial growth factor (VEGF) inhibition. Parsatuzumab is primarily researched for its potential applications in the regulation of angiogenesis and tumor microenvironment modulation.
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