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PAT-048

目录号: A19187
Autotaxin 抑制剂
PAT-048 是一种强效、选择性且可口服的自噬酶抑制剂,能够抑制 IL-6 mRNA 的表达,但在肺纤维化模型中对自噬酶蛋白和肺部溶血磷脂酸(LPA)的产生没有影响。
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规格 价格 库存 数量
1mg
¥1,400.00
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5mg
¥3,500.00
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10mg
¥5,950.00
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25mg
¥11,655.00
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50mg
¥15,225.00
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100mg
¥19,565.00
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生物活性
Discription PAT-048 is a potent, selective and orally active autotaxin inhibitor, inhibits IL-6 mRNA expression, but shows no effect on autotaxin protein and pulmonary lysophosphatidic acid (LPA) production in lung fibrosis model.
产品信息
目录号 A19187
分子式 C22H18ClF2N3O2S
分子量 461.91
CAS号 1359983-15-5
SMILES CCCN1N=CC(N2C3=C(C(SC4=CC=CC(C(O)=O)=C4F)=C2C)C=CC(Cl)=C3F)=C1
其他名称 PAT048, PAT 048
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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