PAT-048
目录号: A19187
Autotaxin 抑制剂
PAT-048 是一种强效、选择性且可口服的自噬酶抑制剂,能够抑制 IL-6 mRNA 的表达,但在肺纤维化模型中对自噬酶蛋白和肺部溶血磷脂酸(LPA)的产生没有影响。
Discription | PAT-048 is a potent, selective and orally active autotaxin inhibitor, inhibits IL-6 mRNA expression, but shows no effect on autotaxin protein and pulmonary lysophosphatidic acid (LPA) production in lung fibrosis model. |
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目录号 | A19187 |
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分子式 | C22H18ClF2N3O2S |
分子量 | 461.91 |
CAS号 | 1359983-15-5 |
SMILES | CCCN1N=CC(N2C3=C(C(SC4=CC=CC(C(O)=O)=C4F)=C2C)C=CC(Cl)=C3F)=C1 |
其他名称 | PAT048, PAT 048 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2