PAT-1251 Hydrochloride

目录号: A21969

LOXL2 inhibitor

PAT-1251 Hydrochloride

PAT-1251 Hydrochloride Chemical Structure

CAS NO. 2098884-53-6

PAT-1251 Hydrochloride is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively).

库存: 现货

规格 价格 数量
1 mg
¥ 3,200.00
5 mg
¥ 9,600.00
10 mg
¥ 16,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PAT-1251 Hydrochloride is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.95 mL 114.73 mL 229.46 mL
0.5 mM 4.59 mL 22.95 mL 45.89 mL
1 mM 2.29 mL 11.47 mL 22.95 mL
5 mM 0.46 mL 2.29 mL 4.59 mL

*The above data is based on the productmolecular weight 435.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21969
作用机制 Inhibitor (抑制剂)
M. Wt 435.8
Formula C18H18ClF4N3O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 2098884-53-6
Synonyms PAT 1251, PAT1251
SMILES O=C(C1=CC=CC(OC2=NC(C(F)(F)F)=CC(CN)=C2)=C1)N3C[C@@H](F)[C@H](O)C3.Cl

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