产品详情
PAT-505 is a potent, selective, noncompetitive and orally available autotaxin inhibitor, with an IC50 of 2 nM in Hep3B cells, 9.7 nM in human blood and 62 nM in mouse plasma.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.1 mL | 105.5 mL | 211.01 mL |
0.5 mM | 4.22 mL | 21.1 mL | 42.2 mL |
1 mM | 2.11 mL | 10.55 mL | 21.1 mL |
5 mM | 0.42 mL | 2.11 mL | 4.22 mL |
*The above data is based on the productmolecular weight 473.92. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A19715 |
---|---|
M. Wt | 473.92 |
Formula | C23H18ClF2N3O2S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1782070-22-7 |
Synonyms | PAT505, PAT 505 |
SMILES | O=C(O)C1=CC=CC(SC2=C(C3CC3)N(C4=CN(CC)N=C4)C5=C2C=CC(Cl)=C5F)=C1F |
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