PAT-505
目录号: A19715
autotaxin 抑制剂
PAT-505 是一种有效的、选择性的、非竞争性的、可口服的自噬酶抑制剂,其在 Hep3B 细胞中的 IC50 为 2 nM,在人血液中为 9.7 nM,在小鼠血浆中为 62 nM。
Discription | PAT-505 is a potent, selective, noncompetitive and orally available autotaxin inhibitor, with an IC50 of 2 nM in Hep3B cells, 9.7 nM in human blood and 62 nM in mouse plasma. | ||
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目录号 | A19715 |
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分子式 | C23H18ClF2N3O2S |
分子量 | 473.92 |
CAS号 | 1782070-22-7 |
SMILES | O=C(O)C1=CC=CC(SC2=C(C3CC3)N(C4=CN(CC)N=C4)C5=C2C=CC(Cl)=C5F)=C1F |
其他名称 | PAT505, PAT 505 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2