Pazopanib HCl (GW786034)

目录号: A10699

VEGFR/PDGFR/FGFR inhibitor

Pazopanib HCl (GW786034) Chemical Structure

CAS NO. 635702-64-6

Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit that blocks tumor growth and inhibits angiogenesis.

库存: 现货

规格 价格 数量
10 mg
¥ 400.00
25 mg
¥ 600.00
50 mg
¥ 1,000.00
100 mg
¥ 1,500.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit that blocks tumor growth and inhibits angiogenesis.
Targets
Target Value
VEGFR1IC50: 10nM
VEGFR2IC50: 30nM
VEGFR3IC50: 47nM
FGFRIC50: 74nM
PDGFRIC50: 84nM
c-KitIC50: 140nM
c-FmsIC50: 146nM
In vitro (25°C) DMSO 17 mg/mL (35.86 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.1 mL 105.49 mL 210.97 mL
0.5 mM 4.22 mL 21.1 mL 42.19 mL
1 mM 2.11 mL 10.55 mL 21.1 mL
5 mM 0.42 mL 2.11 mL 4.22 mL

*The above data is based on the productmolecular weight 474.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10699
MECHANISM OF ACTION Inhibitor
M. Wt 474.0
Formula C21H23N7O2S.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 635702-64-6
Synonyms GW786034, GW-786034
SMILES CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
您还可能对下列产品感兴趣
Keywords:购买 Pazopanib HCl (GW786034) | Pazopanib HCl (GW786034) 供应商 | 订购 Pazopanib HCl (GW786034) | Pazopanib HCl (GW786034) 价格 | Pazopanib HCl (GW786034) 生产商 | 订单 Pazopanib HCl (GW786034) | Pazopanib HCl (GW786034) 代理商 | 购买 635702-64-6| 635702-64-6 供应商 | 订购 635702-64-6 | 635702-64-6 价格 | 635702-64-6 生产商 | 订单 635702-64-6 | 635702-64-6 代理商|buy Pazopanib HCl (GW786034) | Pazopanib HCl (GW786034) Supplier | purchase Pazopanib HCl (GW786034) | Pazopanib HCl (GW786034) cost | Pazopanib HCl (GW786034) manufacturer | order Pazopanib HCl (GW786034) | Pazopanib HCl (GW786034) distributor | buy 635702-64-6| 635702-64-6 Supplier | purchase 635702-64-6 | 635702-64-6 cost | 635702-64-6 manufacturer | order 635702-64-6 | 635702-64-6 distributor
Rewards