PCI-24781 (Abexinostat)

目录号: A10700

HDAC 抑制剂

PCI-24781 (Abexinostat)

PCI-24781 (Abexinostat) Chemical Structure

CAS NO. 783355-60-2

PCI-24781 (Abexinostat)是一种广谱苯基异羟肟酸HDAC抑制剂。

库存: 现货 Shipped in 7-10 Days

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,200.00
50 mg
¥ 3,800.00
100 mg
¥ 6,000.00
10mM * 1mL in DMSO
¥ 1,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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PCI-24781 (Abexinostat)是一种广谱苯基异羟肟酸HDAC抑制剂。
Targets
Target Value
HDAC1ki: 7nM
HDAC3/SMRTki: 8.2nM
HDAC6ki: 17nM
HDAC2ki: 19nM
HDAC10IC50: 24nM
HDAC8IC50: 280nM
In vitro DMSO 80 mg/mL (201.29 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.16 mL 125.82 mL 251.64 mL
0.5 mM 5.03 mL 25.16 mL 50.33 mL
1 mM 2.52 mL 12.58 mL 25.16 mL
5 mM 0.5 mL 2.52 mL 5.03 mL

*The above data is based on the productmolecular weight 397.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10700
作用机制 Inhibitor (抑制剂)
M. Wt 397.4
Formula C21H23N3O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 783355-60-2
Synonyms PCI24781, CRA-024781
SMILES CN(C)CC1=C(OC2=CC=CC=C21)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO

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