PCI-34051

目录号: A11152

HDAC 抑制剂

PCI-34051

PCI-34051 Chemical Structure

CAS NO. 950762-95-5

PCI-34051是一种有效的特异性组蛋白脱乙酰基酶8(HDAC8)抑制剂,其选择性是其他HDAC亚型的200倍以上。

库存: 现货

规格 价格 数量
10 mg
¥ 1,000.00
25 mg
¥ 2,000.00
50 mg
¥ 3,500.00
100 mg
¥ 6,600.00
10mM * 1mL in DMSO
¥ 600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PCI-34051是一种有效的特异性组蛋白脱乙酰基酶8(HDAC8)抑制剂,其选择性是其他HDAC亚型的200倍以上。
Targets
Target Value
HDAC8IC50: 10nM
HDAC6IC50: 2.9μM
HDAC1IC50: 4μM
HDAC10IC50: 13μM
HDAC2IC50: >50μM
HDAC3IC50: >50μM
In vitro (25°C) DMSO 59 mg/mL (199.1 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.75 mL 168.75 mL 337.5 mL
0.5 mM 6.75 mL 33.75 mL 67.5 mL
1 mM 3.37 mL 16.87 mL 33.75 mL
5 mM 0.67 mL 3.37 mL 6.75 mL

*The above data is based on the productmolecular weight 296.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11152
作用机制 Inhibitor (抑制剂)
M. Wt 296.3
Formula C17H16N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 950762-95-5
Synonyms PCI34051
SMILES COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO

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