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PD0166285

目录号: A15863
Wee1/Chk 抑制剂
PD0166285 是一种强效的 Wee1Chk1 抑制剂,具有纳摩尔浓度的活性。PD0166285 是一种新型的 G2 checkpoint 破坏剂。
Grouped product items
规格 价格 库存 数量
1mg
¥315.00
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2mg
¥455.00
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5mg
¥875.00
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10mg
¥1,435.00
现货
25mg
¥3,185.00
现货
50mg
¥4,690.00
现货
100mg
¥6,720.00
现货
500mg
¥13,475.00
现货
10mM * 1mL in DMSO
¥980.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用PD0166285发表的1篇文献
  • Trang H. Nguyen Vu, .et al. , Cancer Sci, 2023, Dec; 114(12): 4664-4676 PMID: 37724648
  • 生物活性
    Discription PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A15863
    分子式 C26H27Cl2N5O2
    分子量 512.43
    CAS号 185039-89-8
    SMILES CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl
    其他名称 PD-0166285, PD 0166285
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 91 mg/mL (177.58 mM)
    Water Insoluble
    Ethanol 91 mg/mL (177.58 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.51 mL 97.57 mL 195.15 mL
    0.5 mM 3.9 mL 19.51 mL 39.03 mL
    1 mM 1.95 mL 9.76 mL 19.51 mL
    5 mM 0.39 mL 1.95 mL 3.9 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

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