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Wee1 抑制剂

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产品目录号: A15863


产品名 目录号 价格 数量
PD0166285 5mg A15863-5
¥ 1,500.00
PD0166285 10mg A15863-10
¥ 2,500.00
PD0166285 25mg A15863-25
¥ 5,500.00



PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.





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Chemical Information

目录号 A15863
Mechanism of action Inhibitor
分子量 512.43
化学分子式 C26H27Cl2N5O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 185039-89-8
Synonyms PD-0166285, PD 0166285
化学名称 6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one


PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.
Wee1 Myt1 Chk1
24 nM72 nM3.4 μM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.51 mL 97.57 mL 195.15mL
0.5 mM 3.9 mL 19.51 mL 39.03 mL
1 mM 1.95 mL 9.76 mL 19.51 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 512.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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