PD0325901

目录号: A10256

MEK inhibitor

PD0325901 Chemical Structure

CAS NO. 391210-10-9

PD0325901 is MEK inhibitor and non-competitive with ATP, Kiapp of 1 nM against activated MEK1 and MEK2.

库存: 现货

规格 价格 数量
5 mg
¥ 450.00
10 mg
¥ 900.00
25 mg
¥ 1,500.00
100 mg
¥ 3,100.00
10mM * 1mL in DMSO
¥ 600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PD0325901 is MEK inhibitor and non-competitive with ATP, Kiapp of 1 nM against activated MEK1 and MEK2.
Targets
MEK (Cell-free assay)
0.33 nM
In vitro DMSO 96 mg/mL (199.09 mM)
Water <1 mg/mL (<1 mM)
Ethanol 40 mg/mL (82.95 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.74 mL 103.69 mL 207.38 mL
0.5 mM 4.15 mL 20.74 mL 41.48 mL
1 mM 2.07 mL 10.37 mL 20.74 mL
5 mM 0.41 mL 2.07 mL 4.15 mL

*The above data is based on the productmolecular weight 482.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10256
MECHANISM OF ACTION Inhibitor
M. Wt 482.2
Formula C16H14F3IN2O4
Solubility DMSO>96mg/mL Water<1mg/mL Ethanol>96mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 391210-10-9
Synonyms N/A
SMILES C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOC[C@@H](CO)O

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